Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28071904 | 1.00 | CYP2C19 (0.42) | CYP2C19MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL1032798 | 0.85 | CYP2C19 (0.43) | CYP2C19MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL1032800 | 0.85 | CYP2C19 (0.43) | CYP2C19MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL7739887 | 0.81 | NAALAD2 (0.46) | CYP2C19GAAKMT2AMEN1HSD17B10 | |
| SCHEMBL7607064 | 0.81 | MME (0.48) | FOLH1 | |
| SCHEMBL7607068 | 0.81 | MME (0.48) | FOLH1 | |
| SCHEMBL29159326 | 0.80 | MEN1 (0.45) | MAPTGAAKMT2AMEN1HSD17B10 | |
| SCHEMBL27548953 | 0.78 | MMP2 (0.42) | CYP2C19MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL10670688 | 0.77 | GAA (0.47) | CYP2C19MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL11386076 | 0.75 | RAB9A (0.54) | CYP2C19KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | claimed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | claimed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | claimed |
| CN-105377878-B | New RhtB protein variant and the method for generating O- phosphoserine using it | CJ第制糖株式会社 | 2018-12-18 | — | — | CN | disclosed |
| WO-2013029648-A1 | NEW AMINOACID COMPOUNDS FOR TREATING TUMOURS AND AUTOIMMUNE DISEASES | ARKE' ORGANICS S.R.L. (IT) | 2013-03-07 | — | — | WO | disclosed |
| US-7015331-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | disclosed |
| US-6939967-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | disclosed |
| US-6756216-B2 | BATCH PROCESSING USING NUCLEOPHILIC COMPOUND | Consortium für elektrochemische Industrie GmbH (DE) | 2004-06-29 | — | — | US | disclosed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | disclosed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | BCAT2, BCAT1, CBS | CYP2C19 1418/4885MAPT 4195/4885KDM4E 1903/4885 |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CBS, BCAT2, BCAT1 | CYP2C19 1585/4885MAPT 3988/4885KDM4E 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.