Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.39 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613888 | 0.87 | OPRM1 (0.49) | PARP1PARP2OPRM1OPRD1ARRB1 | |
| SCHEMBL5828656 | 0.87 | OPRM1 (0.41) | PARP1OPRM1OPRD1OPRK1GAA | |
| SCHEMBL6751101 | 0.86 | PARP1 (0.46) | PARP1PARP2OPRM1OPRD1ARRB1 | |
| SCHEMBL5829605 | 0.85 | PARP1 (0.43) | PARP1PARP2OPRM1OPRD1OPRK1 | |
| SCHEMBL5829936 | 0.85 | PARP2 (0.40) | PARP2OPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL5829663 | 0.84 | DRD4 (0.42) | PARP1PARP2OPRM1OPRD1OPRK1 | |
| SCHEMBL5829612 | 0.82 | OPRD1 (0.48) | OPRM1OPRD1ARRB1OPRK1 | |
| SCHEMBL5829647 | 0.82 | PARP1 (0.42) | PARP1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL5879344 | 0.80 | OPRD1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5630843 | 0.77 | OPRD1 (0.52) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008952-B2 | 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2006-03-07 | — | — | US | claimed |