Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645447 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1HTTPLK1HAO1 | |
| SCHEMBL7884174 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1HTTPLK1HAO1 | |
| SCHEMBL16553310 | 0.79 | LMNA (0.59) | HTTSLC6A4LMNAHSD17B10MEN1 | |
| SCHEMBL2289091 | 0.79 | ALDH1A1 (0.50) | HTTSLC6A4LMNAHSD17B10MEN1 | |
| SCHEMBL442090 | 0.79 | MDM2 (0.59) | HTTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10852929 | 0.79 | TAS1R3 (0.47) | TAS1R3TAS1R1HTTPLK1HAO1 | |
| SCHEMBL904487 | 0.78 | HTT (0.51) | HTTLMNAHSD17B10KDM4EPOLB | |
| SCHEMBL342966 | 0.78 | GSK3B (0.48) | HTTSLC6A4FPR2LMNAHSD17B10 | |
| SCHEMBL891617 | 0.78 | PTPN1 (0.47) | LMNAHSD17B10MEN1KMT2AATM | |
| Fluoride SCHEMBL28046161 | 0.77 | MDM2 (0.57) | HTTLMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101873-B2 | Pyrimidinedione derivatives | BEXEL PHARMACEUTICALS INC. (US) | 2006-09-05 | — | — | US | disclosed |