Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 4/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991959 | 0.86 | TSHR (0.50) | TSHRMAPTRXFP1CETPS1PR2 | |
| SCHEMBL10936592 | 0.86 | CETP (0.46) | TSHRMAPTRXFP1CETPMAPK1 | |
| SCHEMBL8949633 | 0.84 | SIGMAR1 (0.50) | TSHRMAPTRXFP1CETPS1PR2 | |
| SCHEMBL7379078 | 0.83 | TSHR (0.53) | TSHRMAPTRXFP1CETPS1PR2 | |
| SCHEMBL27991950 | 0.81 | TSHR (0.47) | TSHRCETPS1PR2S1PR4S1PR1 | |
| SCHEMBL3743712 | 0.80 | ABCB11 (0.37) | TSHRCETPS1PR2S1PR4S1PR1 | |
| SCHEMBL3421210 | 0.76 | CETP (0.38) | CETPSMN1; SMN2 | |
| SCHEMBL3975163 | 0.75 | MAPT (0.51) | MAPTRXFP1HDAC1HDAC3MAPK1 | |
| SCHEMBL5831419 | 0.75 | LMNA (0.47) | TSHRMAPTRXFP1CETPS1PR2 | |
| SCHEMBL11509944 | 0.75 | CETP (0.49) | TSHRCETPHDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078532-B2 | Process for manufacture of fosinopril sodium | LUPIN LABORATORIES LIMITED (IN) | 2006-07-18 | — | — | US | disclosed |
| US-20040225127-A1 | Process for manufacture of fosinopril sodium | LUPIN LABORATORIES LIMITED (IN) | 2004-11-11 | — | — | US | disclosed |
| US-5739123-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR TREATING CARDIOVASCULAR DISEASES | ZAMBON GROUP S.P.A. (IT) | 1998-04-14 | — | — | US | disclosed |
| EP-0766687-A1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035302-A1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1995-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225127-A1 | Process for manufacture of fosinopril sodium | FOS, FOSB, AGT | TSHR 3065/4885MAPT 2302/4885RXFP1 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.