Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831593 | 0.86 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL5832355 | 0.82 | L3MBTL1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL5831095 | 0.76 | ADRA2A (0.34) | — | |
| SCHEMBL15405496 | 0.75 | NR1H2 (0.33) | EPHX2 | |
| SCHEMBL669702 | 0.70 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL1562731 | 0.70 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL27707269 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL1584727 | 0.69 | GABRA1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL27478342 | 0.69 | GABRA1 (0.37) | GABRA1GABRB2 | |
| SCHEMBL8653206 | 0.68 | GABRA1 (0.32) | GABRA1GABRB2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009015-B2 | Silane compounds with an ortho-substituted aromatic ring directly attached to the silicon atom useful as electron donors in Ziegler-Natta catalysts; makes propylene polymers with high degree of stereoblocks | BASELL TECHNOLOGY COMPANY BV (NL) | 2006-03-07 | — | — | US | disclosed |
| CN-1193046-C | Alpha-olefin polymerization catalyst system containing aromatic silane compound | BASELL TECH CO B V (NL) | 2005-03-16 | — | — | CN | disclosed |
| EP-1157045-B1 | ALPHA-OLEFIN POLYMERIZATION CATALYST SYSTEM WHICH CONTAINS AN AROMATIC SILANE COMPOUND | BASELL POLIOLEFINE SPA (IT) | 2004-10-20 | — | — | EP | disclosed |
| US-6723865-B2 | FOR PRODUCING STEREOBLOCK POLYPROPYLENE | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-04-20 | — | — | US | disclosed |
| US-20020143204-A1 | Alpha-olefin polymerization catalyst system which contains an aromatic silane compound | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2002-10-03 | — | — | US | disclosed |
| CN-1344280-A | Alpha-olefin polymerization catalyst system which contains aromatic silane compound | BASELL TECH CO B V (NL) | 2002-04-10 | — | — | CN | disclosed |
| EP-1157045-A1 | ALPHA-OLEFIN POLYMERIZATION CATALYST SYSTEM WHICH CONTAINS AN AROMATIC SILANE COMPOUND | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| US-20010016635-A1 | Alpha-olefin polymerization catalyst system which contains an aromatic silane compound | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2001-08-23 | — | — | US | disclosed |
| WO-2001046272-A1 | ALPHA-OLEFIN POLYMERIZATION CATALYST SYSTEM WHICH CONTAINS AN AROMATIC SILANE COMPOUND | BASELL TECHNOLOGY COMPANY B.V. (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143204-A1 | Alpha-olefin polymerization catalyst system which contains an aromatic silane compound | OSBP, OXER1, OCIAD1 | GABRA1 2994/4885GABRB2 2757/4885PDK2 3030/4885 |
| US-20010016635-A1 | Alpha-olefin polymerization catalyst system which contains an aromatic silane compound | OSBP, OXER1, OCIAD1 | GABRA1 2994/4885GABRB2 2757/4885PDK2 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.