Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634938 | 0.95 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5388463 | 0.87 | THRB (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL35127 | 0.84 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6381554 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL978174 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16207843 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16207815 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16207723 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28228114 | 0.83 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL98029 | 0.81 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030259-B2 | Process for the preparation of silicone compounds | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050256330-A1 | Process for the preparation of silicone compounds | DOW TORAY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1472264-B1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1472264-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064436-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |
| US-6399212-B1 | COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE | NIPPON SHEET GLASS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1094090-A2 | Silicon dioxide-coated polyolefin resin and process for its production | NIPPON SHEET GLASS CO. LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256330-A1 | Process for the preparation of silicone compounds | ADH1C, ACMSD, SORD | TSHR 3154/4885POLB 512/4885APEX1 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.