SCHEMBL5832737

SCHEMBL5832737

CCOC(C)C(OCC)(OCC)SSC(OCC)(OCC)C(C)OCC.[SiH4]

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3676619 0.98 LMNA (0.38) LMNATHRB
SCHEMBL5832675 0.91 LMNA (0.33) LMNA
SCHEMBL98905 0.89 LMNA (0.35) LMNATHRB
SCHEMBL7631815 0.73 THRB (0.32) LMNATHRB
SCHEMBL15327013 0.73 THRB (0.32) LMNATHRB
SCHEMBL28862837 0.72
SCHEMBL28862947 0.72
SCHEMBL28862839 0.71
SCHEMBL794425 0.70 LMNA (0.43) LMNATHRB
SCHEMBL14537243 0.69 LMNA (0.41) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7030259-B2 Process for the preparation of silicone compounds DOW CORNING TORAY SILICONE CO., LTD. (JP) 2006-04-18 US disclosed
US-20050256330-A1 Process for the preparation of silicone compounds DOW TORAY CO., LTD. (JP) 2005-11-17 US disclosed
EP-1472264-B1 PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS DOW CORNING TORAY SILICONE (JP) 2005-06-15 EP disclosed
EP-1472264-A1 PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS Dow Corning Toray Silicone Co., Ltd. (JP) 2004-11-03 EP disclosed
WO-2003064436-A1 PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256330-A1 Process for the preparation of silicone compounds ADH1C, ACMSD, SORD LMNA 778/4885THRB 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.