Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045807 | 0.84 | GABRA1 (0.45) | GABRA1GABRB2 | |
| SCHEMBL18242067 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2CCR3MGLLCYP24A1 | |
| SCHEMBL8371947 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2CCR3MGLLCYP24A1 | |
| SCHEMBL5892736 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2CCR3MGLLCYP24A1 | |
| SCHEMBL5330754 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2CCR3MGLLCYP24A1 | |
| SCHEMBL18378278 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2CCR3MGLLCYP24A1 | |
| SCHEMBL27496764 | 0.73 | TSHR (0.45) | MAPTL3MBTL1ALDH1A1HTTMEN1 | |
| SCHEMBL434629 | 0.73 | NFE2L2 (0.48) | MAPT | |
| SCHEMBL4073321 | 0.73 | GABRA1 (0.47) | GABRA1GABRB2MAOA | |
| SCHEMBL1149697 | 0.73 | GABRA1 (0.37) | GABRA1GABRB2CCR3MGLLCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009015-B2 | Silane compounds with an ortho-substituted aromatic ring directly attached to the silicon atom useful as electron donors in Ziegler-Natta catalysts; makes propylene polymers with high degree of stereoblocks | BASELL TECHNOLOGY COMPANY BV (NL) | 2006-03-07 | — | — | US | disclosed |
| US-6723865-B2 | FOR PRODUCING STEREOBLOCK POLYPROPYLENE | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-04-20 | — | — | US | disclosed |