Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266618 | 0.88 | SIRT2 (0.44) | SIRT2KMT2AALDH1A1ADRB2MAPT | |
| SCHEMBL3585495 | 0.85 | KDM4E (0.40) | SIRT2KMT2AALDH1A1MAPTFOLH1 | |
| SCHEMBL940131 | 0.84 | ALDH1A1 (0.60) | SIRT2KMT2AALDH1A1ADRB2MAPT | |
| Hydrochloric Acid SCHEMBL28193722 | 0.83 | ALDH1A1 (0.58) | SIRT2KMT2AALDH1A1ADRB2MAPT | |
| SCHEMBL5023477 | 0.82 | KDM4E (0.40) | SIRT2KMT2AALDH1A1MAPTFOLH1 | |
| SCHEMBL29410986 | 0.81 | BID (0.51) | SIRT2KMT2AALDH1A1ADRB2MAPT | |
| SCHEMBL3376462 | 0.81 | SIRT2 (0.50) | SIRT2KMT2AALDH1A1ADRB2MAPT | |
| SCHEMBL27924016 | 0.80 | KDM4E (0.44) | SIRT2KMT2AALDH1A1MAPTFOLH1 | |
| SCHEMBL7479445 | 0.80 | KDM4E (0.44) | SIRT2KMT2AALDH1A1MAPTFOLH1 | |
| SCHEMBL4735612 | 0.78 | ALDH1A1 (0.54) | SIRT2KMT2AALDH1A1ADRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056935-B2 | Rotamase enzyme activity inhibitors | GPI NIL HOLDINGS, INC. (US) | 2006-06-06 | — | — | US | disclosed |
| US-20020052410-A1 | Administering to the animal suffering from neurological disorders an amide compound having an affinity for FKBP-type immunophilins | GLIAMED, INC. | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052410-A1 | Administering to the animal suffering from neurological disorders an amide compound having an affinity for FKBP-type immunophilins | FKBP14, FKBP1A, FKBP2 | SIRT2 2396/4885KMT2A 4124/4885ALDH1A1 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.