SCHEMBL5836617

SCHEMBL5836617

CC1=Cc2c(-c3c(C)cccc3C)cccc2C1[Si](C)(C)C1C(C)=Cc2c(-c3c(C)cccc3C)cccc21

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.33
FGFR1 P11362 1/20 0.31
RAB9A P51151 2/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
NPC1 O15118 1/20 0.30
CASP3 P42574 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453207 0.89 CRHR1 (0.33)
SCHEMBL5836701 0.87 RAB9A (0.37) RAB9ANPC1CASP3SMN1; SMN2SENP8
SCHEMBL5837897 0.86 CNR2 (0.33) HTR2AHTR2CHTR2B
SCHEMBL1454519 0.84 HTR2C (0.31) HTR2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL5168251 0.81
SCHEMBL61908 0.81 PDCD1 (0.34) RAB9AHTR2BNPC1SMN1; SMN2
SCHEMBL29366427 0.81 PDCD1 (0.34) RAB9AHTR2BNPC1SMN1; SMN2
SCHEMBL1454590 0.79 ADORA3 (0.33) RAB9ANPC1SMN1; SMN2
SCHEMBL5837280 0.79 S1PR4 (0.33) RAB9ANPC1CASP3SMN1; SMN2SENP8
Hydrochloric Acid SCHEMBL3822639 0.78 ADRA2A (0.34) RAB9AHTR2BNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
EP-1015463-B1 METHOD FOR PRODUCING METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2002-12-11 EP disclosed