Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827265 | 0.77 | CYP3A4 (0.59) | CYP3A4CDK2NCEH1TSHRALDH1A1 | |
| SCHEMBL9558553 | 0.77 | CYP3A4 (0.59) | CYP3A4CDK2TSHRALDH1A1KMT2A | |
| SCHEMBL5836018 | 0.77 | CYP3A4 (0.59) | CYP3A4CDK2NCEH1TSHRALDH1A1 | |
| SCHEMBL5837648 | 0.76 | CYP3A4 (0.57) | CYP3A4CDK2NCEH1TSHRANO1 | |
| SCHEMBL9636835 | 0.76 | CYP3A4 (0.53) | CYP3A4CDK2NCEH1TSHRANO1 | |
| SCHEMBL12192755 | 0.75 | CDK2 (0.56) | CYP3A4CDK2TSHRKMT2AMEN1 | |
| SCHEMBL1287816 | 0.74 | WDR5 (0.59) | CYP3A4CDK2NCEH1TSHRALDH1A1 | |
| SCHEMBL1646973 | 0.73 | ALDH1A1 (0.41) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL31388678 | 0.73 | TSHR (0.55) | CYP3A4NCEH1TSHRALDH1A1KMT2A | |
| SCHEMBL7170274 | 0.73 | TSHR (0.55) | CYP3A4NCEH1TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056929-B2 | Benzo[b]pyrano[3,2-h]acridin-7-one compounds | LES LABORATOIRES SERVIER (FR) | 2006-06-06 | — | — | US | disclosed |
| US-20040063702-A1 | Benzo[b]pyrano[3,2-h]acridin-7-one compounds | LES LABORATOIRES SERVIER (FR) | 2004-04-01 | — | — | US | disclosed |
| US-6642248-B2 | Antitumor, anticancer agent | LES LABORATORIES SERVIER (FR) | 2003-11-04 | — | — | US | disclosed |
| US-20030073841-A1 | New benzo [b] pyrano [3,2-h] acridin-7-one compounds | LES LABORATOIRES SERVIER (FR) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063702-A1 | Benzo[b]pyrano[3,2-h]acridin-7-one compounds | OXGR1, OXER1, CBR1 | CYP3A4 1557/4885CDK2 3273/4885NCEH1 448/4885 |
| US-20030073841-A1 | New benzo [b] pyrano [3,2-h] acridin-7-one compounds | OXGR1, OXER1, NAT1 | CYP3A4 1270/4885CDK2 2194/4885NCEH1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.