Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592352 | 0.83 | LMNA (0.57) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL5130508 | 0.83 | HTT (0.63) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8631220 | 0.83 | KMT2A (0.76) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL5973256 | 0.81 | CA1 (0.58) | LMNAKMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL4643749 | 0.81 | LMNA (0.58) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL11151702 | 0.81 | KMT2A (0.45) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL11773507 | 0.81 | KMT2A (0.45) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL561023 | 0.81 | KMT2A (0.45) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL819434 | 0.81 | KMT2A (0.66) | LMNAGAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL10593101 | 0.80 | KMT2A (0.57) | LMNAGAAKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357989-A | Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application | 常州强力电子新材料股份有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-105294413-B | Method for preparing aldehyde/ketone by catalyzing alcohol oxidation with iron salt | 浙江工业大学 | 2017-04-12 | — | — | CN | claimed |
| CN-118239850-A | Synthesis and application of alpha-alkyl glycine derivative | 西北师范大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-112939883-B | Preparation method of polysubstituted 1, 3-oxazolidine compound | 兰州大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-113004162-B | Preparation method of asymmetric gem diaryl acetate compound | 苏州大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-115838355-A | 1, 4-disubstituted piperazine-2, 5-diketone derivative, preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-03-24 | — | — | CN | disclosed |
| WO-2023012437-A1 | ANTIBODY-DRUG CONJUGATES | MC SAF (FR) | 2023-02-09 | — | — | WO | disclosed |
| WO-2022090520-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2022-05-05 | — | — | WO | disclosed |
| CN-113004162-A | Preparation method of asymmetric geminal diaryl acetate compound | 苏州大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-112939883-A | Preparation method of polysubstituted 1, 3 oxazolidine compound | 兰州大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-110357989-A | Tertiary amine photosensitizer, preparation method, comprising its photosensitive polymer combination and photosensitive polymer combination application | 常州强力电子新材料股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-105283439-B | The dibenzoylhydrazine of boracic | 英特瑞克斯顿股份有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105294413-B | Method for preparing aldehyde/ketone by catalyzing alcohol oxidation with iron salt | 浙江工业大学 | 2017-04-12 | — | — | CN | disclosed |
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | disclosed |
| CN-1784239-A | Protease inhibitors of coronavirus and SARS-COV and use thereof | CYTOVIA INC (US) | 2006-06-07 | — | — | CN | disclosed |
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |
| US-20040198780-A1 | Inhibitors of cathepsin S | IRM LLC (BM) | 2004-10-07 | — | — | US | disclosed |
| CN-1473157-A | Amide derivatives | ֮����ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| CN-1297354-A | Dipeptide caspase inhibitors and use thereof | CYTOVIA INC (US) | 2001-05-30 | — | — | CN | disclosed |
| EP-0254578-A1 | Antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198780-A1 | Inhibitors of cathepsin S | CTSS, CTSK, CTSE | LMNA 3044/4885GAA 58/4885KMT2A 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.