Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333062 | 0.87 | HTT (0.61) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL2853073 | 0.85 | LMNA (0.73) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL13533942 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL2853072 | 0.85 | LMNA (0.73) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL4968283 | 0.85 | ALDH1A1 (1.00) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL11526803 | 0.85 | HTT (0.71) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL6321203 | 0.84 | FBP1 (0.57) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL29780113 | 0.84 | LMNA (0.63) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL5881545 | 0.84 | LMNA (0.63) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL5523784 | 0.84 | MEN1 (0.67) | ALDH1A1GAALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5310680-A | — | — | None | — | — | JP | disclosed |
| US-20230391760-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-12-07 | — | — | US | disclosed |
| CN-116547279-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20230234943-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234943-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| WO-2021263079-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| US-20200061063-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-02-27 | — | — | US | disclosed |
| CN-106983751-B | Bicyclic substituted uracils and their use | 拜耳医药股份有限公司 | 2020-01-07 | — | — | CN | disclosed |
| US-10300062-B2 | Bicyclically substituted uracils and the use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-28 | — | — | US | disclosed |
| WO-2019049061-A1 | 5-(1 H-BENZO[D]IMIDAZO-2-YL)-PYRIDIN-2-AMINE AND 5-(3H-IMIDAZO[4,5-B]PYRIDIN-6-YL)-PYRIDIN-2-AMINE DERIVATIVES AS C-MYC AND P300/CBP HISTONE ACETYLTRANSFERASE INHIBITORS FOR TREATING CANCER | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-03-14 | — | — | WO | disclosed |
| US-5672759-A | BOARD RANGE OF SHADES OF COLOR EXHIBIT LIGHT RESISTANCE, WASHFASTNESS, WEATHERPROOFING AND RESISTANCE TO VARIOUS TREATMENT TO WHICH HAIR MAY BE SUBJECTED | L'OREAL (FR) | 1997-09-30 | — | — | US | disclosed |
| US-5534037-A | Dye composition for keratinic fibres containing sulfured metaphenylenediamines, dyeing process and new sulfured metaphenylenediamines and preparation method thereof | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0547414-B1 | Process for the preparation of N-substituted nitro-p-phenylenediamines | HOECHST AG (DE) | 1996-03-20 | — | — | EP | disclosed |
| EP-0586648-B1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF | OREAL (FR) | 1995-12-06 | — | — | EP | disclosed |
| US-5414128-A | Dehydrofluorination for amination | CASSELLA AG (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0586648-A1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF. | OREAL (FR) | 1994-03-16 | — | — | EP | disclosed |
| JP-H05310680-A | 5-ACETYLAMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUT CO LTD | 1993-11-22 | — | — | JP | disclosed |
| WO-1993016990-A1 | DYE COMPOSITION FOR KERATINIC FIBRES CONTAINING SULFURED METAPHENYLENEDIAMINES, DYEING PROCESS AND NEW SULFURED METAPHENYLENEDIAMINES AND PREPARATION METHOD THEREOF | L'OREAL (FR) | 1993-09-02 | — | — | WO | disclosed |
| EP-0547414-A2 | Process for the preparation of N-substituted nitro-p-phenylenediamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |
| US-4665083-A | ANTIDEPRESSANT, ANTIEPILEPTIC, SPASMOLYTIC, ANTIPARKINSONIC | EGIS GYOGYSZERGYAR (HU) | 1987-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234943-A1 | TREX1 INHIBITORS AND USES THEREOF | FEN1, ERCC4, DCLRE1B | ALDH1A1 1451/4885GAA 125/4885LMNA 387/4885 |
| US-20230391760-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | ALDH1A1 840/4885GAA 1083/4885LMNA 3670/4885 |
| US-10300062-B2 | Bicyclically substituted uracils and the use thereof | UNG, UMPS, TYMP | ALDH1A1 437/4885GAA 517/4885LMNA 2094/4885 |
| US-20200061063-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | UNG, UMPS, TYMP | ALDH1A1 437/4885GAA 517/4885LMNA 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.