SCHEMBL5843779

SCHEMBL5843779

CCc1c(OCCC(C)CC(C)(C)C)c(C(=O)O)c(CC)c(OCCC(C)CC(C)(C)C)c1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
EGFR P00533 1/20 0.31
PLA2G1B P04054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843785 0.80 EGFR (0.36) MAPK1EGFR
SCHEMBL5840947 0.71 TSHR (0.40) MAPK1EGFR
SCHEMBL9058674 0.70 MAPK1 (0.68) MAPK1
SCHEMBL668868 0.69 PLA2G2A (0.50) THRATHRB
SCHEMBL17186650 0.68 THRA (0.40) THRATHRB
SCHEMBL5531082 0.68 EGFR (0.33) EGFR
SCHEMBL5932536 0.68 EGFR (0.39) EGFR
SCHEMBL113147 0.68 ALOX15 (0.53) EGFR
SCHEMBL8100381 0.67 PLA2G2A (0.41) THRATHRB
SCHEMBL8106324 0.67 PLA2G2A (0.41) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105633-B2 Soluble poly(aryl-oxadiazole) conjugated polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-09-12 US disclosed
US-20050156516-A1 Soluble poly(aryl-oxadiazole) conjugated polymers WANG HAILIANG (US) 2005-07-21 US disclosed
US-6864352-B2 Soluble poly(aryl-oxadiazole) conjugated polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-08 US disclosed
EP-1274760-B1 SOLUBLE POLY(ARYL-OXADIAZOLE) CONJUGATED POLYMERS DUPONT DISPLAYS INC (US) 2004-03-24 EP disclosed
US-20030023029-A1 Soluble poly(aryl-oxadiazole) conjugated polymers DUPONT DISPLAYS, INC. 2003-01-30 US disclosed
EP-1274760-A2 SOLUBLE POLY(ARYL-OXADIAZOLE) CONJUGATED POLYMERS DuPont Displays, Inc. (US) 2003-01-15 EP disclosed
WO-2001077203-A2 SOLUBLE POLY(ARYL-OXADIAZOLE) CONJUGATED POLYMERS DUPONT DISPLAYS, INC. (US) 2001-10-18 WO disclosed