Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106324 | 1.00 | PLA2G2A (0.41) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL668868 | 0.87 | PLA2G2A (0.50) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL17186650 | 0.85 | THRA (0.40) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL7759784 | 0.84 | ALDH1A1 (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL17186600 | 0.84 | PLA2G2A (0.37) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL7754588 | 0.84 | ALDH1A1 (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL8100384 | 0.79 | PTPN11 (0.37) | PLA2G2ATSHR | |
| SCHEMBL8106327 | 0.79 | PTPN11 (0.37) | PLA2G2ATSHR | |
| SCHEMBL5587043 | 0.74 | PLA2G2A (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL5589712 | 0.74 | PLA2G2A (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |