Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100381 | 1.00 | PLA2G2A (0.41) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL668868 | 0.87 | PLA2G2A (0.50) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL17186650 | 0.85 | THRA (0.40) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL7759784 | 0.84 | ALDH1A1 (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL17186600 | 0.84 | PLA2G2A (0.37) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL7754588 | 0.84 | ALDH1A1 (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL8100384 | 0.79 | PTPN11 (0.37) | PLA2G2ATSHR | |
| SCHEMBL8106327 | 0.79 | PTPN11 (0.37) | PLA2G2ATSHR | |
| SCHEMBL5587043 | 0.74 | PLA2G2A (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA | |
| SCHEMBL5589712 | 0.74 | PLA2G2A (0.44) | PLA2G2ATP53TSHRPLA2G4BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10923662-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
| EP-3131898-B1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LTD (GB) | 2020-03-18 | — | — | EP | disclosed |
| EP-3362434-B1 | CROSS-LINKABLE CHARGE TRANSPORT MATERIALS | LOMOX LTD (GB) | 2019-08-28 | — | — | EP | disclosed |
| US-20180309064-A1 | CROSS-LINKABLE CHARGE TRANSPORT MATERIALS | LOMOX LIMITED (GB) | 2018-10-25 | — | — | US | disclosed |
| US-10084137-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2018-09-25 | — | — | US | disclosed |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2018-09-13 | — | — | US | disclosed |
| EP-3362434-A1 | CROSS-LINKABLE CHARGE TRANSPORT MATERIALS | Lomox Limited (GB) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017064490-A1 | CROSS-LINKABLE CHARGE TRANSPORT MATERIALS | LOMOX LIMITED (GB) | 2017-04-20 | — | — | WO | disclosed |
| EP-3131898-A1 | FLUOROALKYLFLUORENE DERIVATIVES | Lomox Limited (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2017-02-02 | — | — | US | disclosed |
| WO-2015159098-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2015-10-22 | — | — | WO | disclosed |
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10084137-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | PLA2G2A 1082/4885TP53 3414/4885TSHR 3720/4885 |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | PLA2G2A 1082/4885TP53 3414/4885TSHR 3720/4885 |
| US-20180309064-A1 | CROSS-LINKABLE CHARGE TRANSPORT MATERIALS | CHRM1, CHRM2, SLC43A1 | PLA2G2A 621/4885TP53 4241/4885TSHR 1917/4885 |
| US-10923662-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | PLA2G2A 1082/4885TP53 3414/4885TSHR 3720/4885 |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | PLA2G2A 1082/4885TP53 3414/4885TSHR 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.