Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514361 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4KIF11SYKTAAR1 | |
| SCHEMBL1052063 | 0.86 | DPP4 (0.50) | TAAR1ALDH1A1DPP4F2 | |
| SCHEMBL1455757 | 0.86 | DPP4 (0.50) | TAAR1ALDH1A1DPP4F2 | |
| SCHEMBL40002 | 0.86 | DPP4 (0.50) | TAAR1ALDH1A1DPP4F2 | |
| Hydrochloric Acid SCHEMBL8390398 | 0.84 | DPP4 (0.48) | TAAR1ALDH1A1DPP4F2 | |
| Hydrochloric Acid SCHEMBL4708717 | 0.84 | DPP4 (0.48) | TAAR1ALDH1A1DPP4F2 | |
| Hydrochloric Acid SCHEMBL5845127 | 0.84 | DPP4 (0.48) | TAAR1ALDH1A1DPP4F2 | |
| SCHEMBL4492399 | 0.76 | SYK (0.39) | SYKPTPN5 | |
| SCHEMBL4503752 | 0.76 | SYK (0.39) | SYKPTPN5 | |
| SCHEMBL28933413 | 0.76 | KIF11 (0.48) | CHRNB2CHRNA4KIF11TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7154005-B2 | Synthesis of alpha fluoroalkyl amines | MERCK FROSST CANADA, LTD. (CA) | 2006-12-26 | — | — | US | disclosed |
| US-20060052642-A1 | Synthesis of alpha fluoroalkyl amines | MERCK CANADA INC. (CA) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052642-A1 | Synthesis of alpha fluoroalkyl amines | ADH5, ADH1C, INMT | CHRNB2 1739/4885CHRNA4 1728/4885KIF11 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.