SCHEMBL5844129

SCHEMBL5844129

CCOC(CC=O)c1c[c]c(Cl)cc1C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8808365 0.73 FFAR1 (0.31)
SCHEMBL7740209 0.72
SCHEMBL5844125 0.72 GPR35 (0.38)
SCHEMBL5843253 0.63 PTGS2 (0.33)
SCHEMBL5843249 0.63 PTGS2 (0.33)
SCHEMBL5842695 0.62 KDM4E (0.39)
SCHEMBL5843327 0.62 TRPV4 (0.34)
SCHEMBL5843665 0.61 ALDH1A1 (0.36)
SCHEMBL5843414 0.61 TRPV4 (0.38)
SCHEMBL5843075 0.61 XDH (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012041-B2 Phenylpyridazinones BAYER AG (DE) 2006-03-14 US disclosed
US-20030119673-A1 Phenylpyridazinones LINKER KARL-HEINZ (DE) 2003-06-26 US disclosed
US-6551963-B1 For controlling unwanted vegetation BAYER AKTIENGESELLSCHAFT (DE) 2003-04-22 US disclosed