Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843334 | 1.00 | GAA (0.53) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL5843337 | 1.00 | GAA (0.53) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL27628501 | 0.83 | ALDH1A1 (0.59) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL16379201 | 0.81 | MEN1 (0.56) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL2172551 | 0.80 | MAPT (0.58) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL2172548 | 0.80 | MAPT (0.58) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL28045428 | 0.78 | PTGS2 (0.67) | GAAMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2384404 | 0.75 | CYP3A4 (0.63) | GAAMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6530102 | 0.74 | MAPT (0.50) | GAAMAPTMEN1KMT2AGFER | |
| SCHEMBL6530099 | 0.74 | MAPT (0.50) | GAAMAPTMEN1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153815-B2 | Insecticide containing hydrazone derivative as the active ingredient and novel hydrazone derivative | NIHON NOHYAKU CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | NIHON NOHYAKU CO., LTD (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-1470752-A1 | INSECTICIDES CONTAINING HYDRAZONE DERIVATIVES AS THE ACTIVE INGREDIENT AND NOVEL HYDRAZONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | DDT, AOX1, HAX1 | GAA 2767/4885MAPT 4852/4885MEN1 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.