Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134704 | 0.78 | CYP3A4 (0.48) | CYP3A4KDM4EACHEABCG2MAPT | |
| SCHEMBL584570 | 0.73 | KDM4E (0.41) | CYP3A4KDM4EACHECYP1A2MAPT | |
| SCHEMBL8930679 | 0.71 | ABCG2 (0.53) | CYP3A4ABCG2CYP1A2MAPTALDH1A1 | |
| SCHEMBL583885 | 0.69 | PTGS2 (0.38) | CYP3A4ABCG2CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL24434308 | 0.67 | CYP3A4 (0.56) | CYP3A4ACHEABCG2CYP1A2MAPT | |
| SCHEMBL20963316 | 0.65 | CYP2D6 (0.47) | CYP3A4KDM4EACHEALDH1A1HSD17B10 | |
| SCHEMBL12341987 | 0.65 | KDM4E (0.50) | CYP3A4KDM4EACHEMAPTALDH1A1 | |
| SCHEMBL5768129 | 0.64 | MAPT (0.47) | CYP3A4KDM4EABCG2MAPTALDH1A1 | |
| SCHEMBL18873211 | 0.63 | CYP3A4 (0.41) | CYP3A4ABCG2CYP1A2MAPTALDH1A1 | |
| SCHEMBL20749426 | 0.62 | KDM4E (0.33) | KDM4ECA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
| EP-2416879-A1 | CYCLIC IMIDATE LIGANDS | Universiteit Gent (BE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115903-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | CYP3A4 751/4885KDM4E 1055/4885ACHE 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.