SCHEMBL5846178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14689801	0.83	HSD17B10 (0.51)	HCRTR2KDM4ENOTUMALDH1A1TSHR
	SCHEMBL1057318	0.81	ADRB1 (0.50)	HCRTR2KDM4ELMNAADRB1NOTUM
	SCHEMBL27937043	0.80	HCRTR2 (0.38)	HCRTR2ALDH1A1HTT
	SCHEMBL22663406	0.78	KDM4E (0.50)	KDM4ELMNAADRB1NOTUMALDH1A1
	SCHEMBL2165481	0.76	ALDH1A1 (0.67)	KDM4EALDH1A1TSHR
	SCHEMBL21682871	0.76	HRH3 (0.43)	ALDH1A1HTT
	SCHEMBL22888	0.75	KMT2A (0.50)	KDM4ELMNAADRB1NOTUMCARM1
	SCHEMBL21668750	0.75	NOTUM (0.54)	HCRTR2KDM4ELMNAADRB1NOTUM
	SCHEMBL22597892	0.75	POLB (0.56)	KDM4ELMNAALDH1A1RAB9AHTT
	SCHEMBL20755234	0.75	ADRB1 (0.50)	KDM4ELMNAADRB1NOTUMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.