Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 3/20 | 0.35 |
| ▸ | MC3R | P41968 | 3/20 | 0.35 |
| ▸ | MC1R | Q01726 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127933 | 0.78 | BCHE (0.44) | BCHEBTKPARP1 | |
| SCHEMBL5844838 | 0.74 | MC3R (0.53) | BDKRB2MC4RMC3RMC1R | |
| SCHEMBL5844739 | 0.72 | ABCB1 (0.57) | BDKRB2DRD2DRD3ABCB1BCHE | |
| SCHEMBL5844741 | 0.72 | ABCB1 (0.57) | BDKRB2DRD2DRD3ABCB1BCHE | |
| SCHEMBL178628 | 0.69 | ABCB1 (0.44) | BDKRB2ABCB1 | |
| SCHEMBL5844869 | 0.68 | PABPC1 (0.47) | MC4RMC3RMC1RABCB1 | |
| SCHEMBL13625881 | 0.68 | BDKRB2 (0.52) | BDKRB2DRD2DRD3ABCB1 | |
| SCHEMBL3140842 | 0.68 | ALDH1A1 (0.35) | BTKPARP1 | |
| SCHEMBL5996402 | 0.64 | BDKRB2 (0.47) | BDKRB2MC4RMC3RMC1RABCB1 | |
| SCHEMBL3140703 | 0.64 | PARP1 (0.43) | BTKPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132539-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-20060247224-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | disclosed |
| US-20050010031-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010031-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | BDKRB2 33/4885DRD2 346/4885DRD3 168/4885 |
| US-20060247224-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | BDKRB2 33/4885DRD2 325/4885DRD3 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.