Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CD69 | Q07108 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509584 | 0.89 | KMT2A (0.60) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL7824239 | 0.88 | KDM4E (0.60) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL1145948 | 0.87 | KMT2A (0.62) | KMT2AKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8414412 | 0.83 | PTGDR2 (0.57) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL29502958 | 0.83 | KDM4E (0.73) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL341639 | 0.83 | KDM4E (0.73) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL7527833 | 0.81 | ABCB1 (0.56) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL6563571 | 0.81 | KDM4E (0.65) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL20509554 | 0.81 | ALDH1A1 (0.60) | KMT2AKDM4EALDH1A1HPGDCD69 | |
| SCHEMBL28731750 | 0.81 | KMT2A (0.77) | KMT2AKDM4EALDH1A1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2005-01-20 | — | — | US | claimed |
| US-6803395-B2 | POLYSILOXANE HAVING THEREON A HYDROPHILIC MOIETY AND A LIGHTFASTNESS MOIETY | XEROX CORPORATION | 2004-10-12 | — | — | US | claimed |
| US-20030137570-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-24 | — | — | US | claimed |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-17 | — | — | US | claimed |
| US-20030119940-A1 | Ink composition with improved lightfastness | XEROX CORPORATION | 2003-06-26 | — | — | US | claimed |
| US-6569511-B1 | Polysiloxane having a hydrophilic moiety and a lightfastness moiety; ink jet coating | XEROX CORPORATION | 2003-05-27 | — | — | US | claimed |
| US-7074853-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| US-6861458-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2005-03-01 | — | — | US | disclosed |
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2005-01-20 | — | — | US | disclosed |
| US-6803395-B2 | POLYSILOXANE HAVING THEREON A HYDROPHILIC MOIETY AND A LIGHTFASTNESS MOIETY | XEROX CORPORATION | 2004-10-12 | — | — | US | disclosed |
| US-20030137570-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-24 | — | — | US | disclosed |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-17 | — | — | US | disclosed |
| US-20030119940-A1 | Ink composition with improved lightfastness | XEROX CORPORATION | 2003-06-26 | — | — | US | disclosed |
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-5686633-A | PHOTOSTABILIZERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0373574-B1 | Inks, especially for ink jet printing | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| EP-0373573-B1 | Recording material for ink jet printing | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5098477-A | Aromatic ether derivatives as light stabilizers for organic materials | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |
| US-5073448-A | Containing light stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0373574-A1 | Inks, especially for ink jet printing | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | LRRFIP1, LRRC59, MMS19 | KMT2A 1571/4885KDM4E 1625/4885ALDH1A1 656/4885 |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | ITGA1, ITGB1, ITGB8 | KMT2A 1558/4885KDM4E 1482/4885ALDH1A1 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.