Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MC4R | P32245 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490484 | 0.85 | ADRB1 (0.47) | GAAMAPTMC4RL3MBTL1ALDH1A1 | |
| SCHEMBL6569082 | 0.83 | NPC1 (0.63) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL8142448 | 0.82 | GAA (0.51) | GAANPC1MAPTNPSR1MC4R | |
| Hydrochloric Acid SCHEMBL10728839 | 0.81 | NPC1 (0.61) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11037115 | 0.81 | NPC1 (0.60) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL27475740 | 0.81 | NPC1 (0.65) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11665416 | 0.80 | NPC1 (0.59) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL15372278 | 0.80 | NPC1 (0.63) | GAANPC1MAPTNPSR1L3MBTL1 | |
| SCHEMBL227731 | 0.79 | NPC1 (0.71) | GAANPC1NPSR1L3MBTL1ATM | |
| SCHEMBL1715918 | 0.79 | NPC1 (0.71) | GAANPC1NPSR1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384708-A | Preparation method for (S)-(+)-1-(2-piperidine phenyl)-3-methyl n-butylamine | Henan purui pharmaceutical co ltd | 2016-03-09 | — | — | CN | disclosed |
| WO-2007104359-A1 | SYNTHESIS OF AMINES WITH YTTERBIUM LEWIS ACIDS | JACOBS UNIVERSITY BREMEN GGMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104357-A1 | SYNTHESIS OF AMINES WITH CATALYTIC AMOUNTS OF MILD LEWIS ACIDS | JACOBS UNIVERSITY BREMEN GGMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
| US-7041830-B2 | Process for preparing (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-09 | — | — | US | disclosed |
| US-20040192921-A1 | Process for preparing (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-09-30 | — | — | US | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6143769-A | ENANTIOMORPH | KARL THOMAE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-6025531-A | REACTING A PROCHIRAL KETONE WITH A MIXTURE BORON-CONTAINING COMPOUNDS HAVING A BORANE REACTION PRODUCT FROM OPTICALLY ACTIVE BETA-AMINOALCOHOL AND A BORON HYDRIDE OR A METAL BOROHYDRIDE, AND AN OPTICALLY ACTIVE OXAZABOROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-15 | — | — | US | disclosed |
| CN-1048722-C | (S)(+)-2-Ethoxy-4-[N-[1-(2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbonylmethyl]-benzoic acid, pharmaceutical compositions containing compound and processes for preparation thereof | THOMAE GMBH DR K (DE) | 2000-01-26 | — | — | CN | disclosed |
| EP-0965591-A1 | (s)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine, its salts, synthesis and use in the long term therapy of diabetes mellitus | Boehringer Ingelheim Pharma KG (DE) | 1999-12-22 | — | — | EP | disclosed |
| EP-0589874-B1 | USE OF (S)(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID FOR THE PREPARATION OF A LONGLASTING ANTIDIABETIC MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-09-08 | — | — | EP | disclosed |
| US-5801280-A | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0736509-A2 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5312924-A | Compounds for lowering blood sugar and effecting metabolism | DR. KARL THOMAE GMBH (DE) | 1994-05-17 | — | — | US | disclosed |
| EP-0589874-A1 | (S)(+)-2-ETHOXY-4- N- 1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID | Dr. Karl Thomae GmbH (DE) | 1994-04-06 | — | — | EP | disclosed |
| CN-1068820-A | (S) (+)-2-oxyethyl group-4-[N-[1-(2-piperidino-phenyl)-3-methyl isophthalic acid-butyl] amino carbonyl methyl] phenylformic acid, contain pharmaceutical composition of this compound and preparation method thereof | THOMAE GMBH DR K (DE) | 1993-02-10 | — | — | CN | disclosed |
| WO-1993000337-A1 | (S)(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID | DR. KARL THOMAE GMBH (DE) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192921-A1 | Process for preparing (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine | GPR119, GLP1R, IRS1 | GAA 646/4885NPC1 1778/4885MAPT 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.