Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.53 |
| ▸ | RELA | Q04206 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13528421 | 0.92 | L3MBTL1 (0.82) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30612644 | 0.87 | L3MBTL1 (1.00) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1634416 | 0.87 | L3MBTL1 (1.00) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14790239 | 0.85 | L3MBTL1 (0.57) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29442076 | 0.84 | NPC1 (0.61) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9105844 | 0.84 | NPC1 (0.61) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL903255 | 0.84 | NPC1 (0.61) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| Iodide SCHEMBL8417295 | 0.82 | NPC1 (0.59) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30385875 | 0.82 | KDM4E (0.58) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28874458 | 0.82 | ALDH1A1 (0.56) | L3MBTL1GAASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758398-B1 | SUBSTITUTED N- [1-CYANO-2- (PHENYL) ETHYL]-2-AZABICYCLO [2.2.1]HEPTANE-3-CARBOXAMIDE INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |
| EP-1306131-B1 | Cross-coupling process using a catalyst comprising a cyclic nitrogen ligand | SUMITOMO CHEMICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-20060111593-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-05-25 | — | — | US | disclosed |
| US-7041856-B2 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20030162950-A1 | Coupling catalyst and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-28 | — | — | US | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162950-A1 | Coupling catalyst and process using the same | NOD1, PYM1, C9 | L3MBTL1 3554/4885GAA 4153/4885SMN1; SMN2 990/4885 |
| US-20060111593-A1 | Coupling catalyst and process using the same | RPL22, C9, RBM22 | L3MBTL1 3379/4885GAA 3810/4885SMN1; SMN2 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.