Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14956732 | 0.81 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1CYP2C19IDH1 | |
| SCHEMBL14956800 | 0.79 | ALDH1A1 (0.30) | ALDH1A1L3MBTL1CYP2C19 | |
| SCHEMBL28014249 | 0.77 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL9862807 | 0.75 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1CYP2C19IDH1 | |
| SCHEMBL9715861 | 0.72 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1IDH1 | |
| SCHEMBL8770165 | 0.72 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1IDH1 | |
| SCHEMBL15848029 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1CYP2C19IDH1 | |
| SCHEMBL5854140 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL860549 | 0.70 | CYP2C19 (0.36) | ALDH1A1CYP2C19 | |
| Fluoride SCHEMBL27912992 | 0.69 | CYP2C19 (0.35) | ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087776-B2 | Silanol enzyme inhibitors | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-08-08 | — | — | US | disclosed |
| US-6960678-B2 | Silanol enzyme inhibitors | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2005-11-01 | — | — | US | disclosed |
| EP-1019533-B1 | SILANOL ENZYME INHIBITORS | UNIV NEW YORK STATE RES FOUND (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20050171059-A1 | Silanol enzyme inhibitors | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK. | 2005-08-04 | — | — | US | disclosed |
| US-6441212-B1 | SILANEDIOL TRIMER OR LARGER MOIETY CONTAINING AT LEAST ONE AMINO OR AMIDO GROUP; ISOSTERES THAT ASPARTIC PROTEASES ACT UPON; NOT CLEAVED UNDER ENZYMATIC CONDITIONS; HUMAN IMMUNODEFICIENCY VIRUS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-08-27 | — | — | US | disclosed |
| US-5760019-A | INHIBIT PROTEASE ENZYMES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171059-A1 | Silanol enzyme inhibitors | CMA1, CTSS, SERPINB1 | ALDH1A1 830/4885L3MBTL1 1632/4885CYP2C19 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.