SCHEMBL8770165

SCHEMBL8770165

C=CCC[SiH](C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDH1 O75874 1/20 0.32
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MMP1 P03956 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769557 0.88 ALDH1A1 (0.34) ALDH1A1ACHEL3MBTL1IDH1TSHR
SCHEMBL8992328 0.78 ALDH1A1 (0.33) ALDH1A1MAPTTSHR
SCHEMBL9862807 0.78 ALDH1A1 (0.34) ALDH1A1ACHEMAPTL3MBTL1IDH1
SCHEMBL9715861 0.75 ALDH1A1 (0.33) ALDH1A1L3MBTL1IDH1TSHR
SCHEMBL15848029 0.75 ALDH1A1 (0.36) ALDH1A1ACHEMAPTL3MBTL1IDH1
SCHEMBL8992405 0.73 TP53 (0.36) ALDH1A1KDM4E
SCHEMBL5852167 0.72 ALDH1A1 (0.31) ALDH1A1L3MBTL1IDH1
SCHEMBL14956732 0.72 ALDH1A1 (0.31) ALDH1A1L3MBTL1IDH1
SCHEMBL28014249 0.72 ALDH1A1 (0.32) ALDH1A1L3MBTL1
SCHEMBL9746880 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604401-B1 Production of a catalyst component for producing crystalline polymers CHISSO CORP (JP) 1997-09-24 EP disclosed
EP-0395391-B1 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0404519-B1 A process for producing a high-stiffness polypropylene CHISSO CORP (JP) 1996-08-07 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed