Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853022 | 0.91 | ALOX5 (0.35) | GAAMAPTADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL5856408 | 0.89 | ADORA1 (0.36) | GAAADORA3ADORA1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5852857 | 0.88 | EPHX2 (0.38) | ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5853189 | 0.87 | EPHX2 (0.40) | ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5854255 | 0.87 | EPHX2 (0.40) | ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5853444 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL5852962 | 0.84 | PAX3 (0.33) | GAAMAPTALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL5854352 | 0.83 | ADORA1 (0.31) | ADORA1 | |
| Hydrochloric Acid SCHEMBL5853572 | 0.81 | HPGD (0.39) | GAAMAPTALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL5854883 | 0.81 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |