Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697479 | 0.81 | CES2 (0.61) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL29442433 | 0.80 | MAPT (0.58) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL22215942 | 0.80 | MAPT (0.58) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL11007079 | 0.80 | MAPT (0.63) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL11007552 | 0.80 | MAPT (0.63) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL13893380 | 0.79 | CES2 (0.59) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL6244793 | 0.79 | ALDH1A1 (0.61) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL22462223 | 0.78 | MAPT (0.66) | CES2CES1MAPTLMNAKDM4E | |
| SCHEMBL30668590 | 0.78 | MAPT (0.66) | CES2CES1MAPTLMNAKDM4E | |
| 2-Picolinic Acid SCHEMBL2148120 | 0.78 | LMNA (0.80) | CES2CES1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598851-A | 5-Aminoindole chalcone compound and preparation method and application thereof | 平顶山学院 | 2024-09-06 | — | — | CN | claimed |
| CN-114258432-A | Method for predicting drug responsiveness in cancer patients | 肿瘤学风险公司 | 2022-03-29 | — | — | CN | claimed |
| WO-2012145069-A2 | MATERIALS AND METHODS USEFUL TO INDUCE CELL DEATH VIA METHUOSIS | THE UNIVERSITY OF TOLEDO (US) | 2012-10-26 | — | — | WO | claimed |
| EP-2416717-A1 | MECHANICAL APPARATUS AND METHOD FOR DELIVERING MATERIALS INTO THE INTER-VERTEBRAL BODY SPACE FOR NUCLEUS REPLACEMENT | Yurek, Matthew (US) | 2012-02-15 | — | — | EP | claimed |
| US-20110270399-A1 | Mechanical Apparatus and Method for Artificial Disc Fusion and Nucleus Replacement | Ouroboros Medical, Inc. | 2011-11-03 | — | — | US | claimed |
| US-8021426-B2 | Mechanical apparatus and method for artificial disc replacement | Ouroboros Medical, Inc. | 2011-09-20 | — | — | US | claimed |
| US-20110190894-A1 | Mechanical Apparatus and Method for Artificial Disc Replacement | Ouroboros Medical, Inc. | 2011-08-04 | — | — | US | claimed |
| US-20110190895-A1 | Mechanical Apparatus and Method for Artificial Disc Replacement | Ouroboros Medical, Inc. | 2011-08-04 | — | — | US | claimed |
| US-7988735-B2 | Mechanical apparatus and method for delivering materials into the inter-vertebral body space for nucleus replacement | Ouroboros Medical, Inc. | 2011-08-02 | — | — | US | claimed |
| WO-2010077934-A1 | MECHANICAL APPARATUS AND METHOD FOR DELIVERING MATERIALS INTO THE INTER-VERTEBRAL BODY SPACE FOR NUCLEUS REPLACEMENT | YUREK MATTHEW (US) | 2010-07-08 | — | — | WO | claimed |
| EP-1328221-A4 | DEVICES AND METHOD FOR NUCLEUS PULPOSUS AUGMENTATION AND RETENTION | INTRINSIC THERAPEUTICS INC (US) | 2007-04-04 | — | — | EP | claimed |
| US-20060287727-A1 | Mechanical apparatus and method for artificial disc replacement | OUROBOROS, INC. A DELAWARE CORPORATION | 2006-12-21 | — | — | US | claimed |
| US-20060287726-A1 | Mechanical apparatus and method for artificial disc replacement | OUROBOROS, INC. A DELAWARE CORPORATION | 2006-12-21 | — | — | US | claimed |
| US-20060287730-A1 | Mechanical apparatus and method for artificial disc replacement | OUROBOROS, INC. A DELAWARE CORPORATION | 2006-12-21 | — | — | US | claimed |
| US-20050021088-A1 | Systems containing temperature regulated medical devices, and methods related thereto | TRITON BIOSYSTEMS, INC. | 2005-01-27 | — | — | US | claimed |
| EP-1450711-A1 | SYSTEMS CONTAINING TEMPERATURE REGULATED MEDICAL DEVICES, AND METHODS RELATED THERETO | Triton Biosystems Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| EP-1328221-A2 | DEVICES AND METHOD FOR NUCLEUS PULPOSUS AUGMENTATION AND RETENTION | Intrinsic Therapeutics, Inc. (US) | 2003-07-23 | — | — | EP | claimed |
| WO-2003037202-A1 | SYSTEMS CONTAINING TEMPERATURE REGULATED MEDICAL DEVICES, AND METHODS RELATED THERETO | TRITON BIOSYSTEMS INC. (US) | 2003-05-08 | — | — | WO | claimed |
| US-20020151979-A1 | Devices and method for nucleus pulposus augmentation and retention | CRG SERVICING LLC | 2002-10-17 | — | — | US | claimed |
| WO-2002054978-A2 | DEVICES AND METHOD FOR NUCLEUS PULPOSUS AUGMENTATION AND RETENTION | INTRINSIC ORTHOPEDICS INC (US) | 2002-07-18 | — | — | WO | claimed |