Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848427 | 0.81 | CA1 (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL109451 | 0.80 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9311265 | 0.77 | CA12 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8459393 | 0.77 | HPGD (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL5856774 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP2C19 | |
| SCHEMBL5857494 | 0.76 | HPGDS (0.33) | CA12CA1CA2CA9CA14 | |
| Hydrazine SCHEMBL10771056 | 0.76 | CA12 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28259138 | 0.75 | CA12 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25780247 | 0.75 | CA12 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28259082 | 0.75 | CA12 (0.50) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115595-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| EP-1357123-B1 | Novel carbapenem, medical and antibacterial comprisisng the same, and uses thereof | SUMITOMO PHARMA (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1535924-A1 | Novel carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-20040063683-A1 | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1357123-A1 | NOVEL CARBAPENEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063683-A1 | Novel carbapenem compounds | PTMS, PNISR, LRPPRC | CA12 4291/4885CA1 4780/4885CA2 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.