Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347522 | 0.81 | TSHR (0.37) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21848427 | 0.81 | CA1 (0.52) | TSHRCA1CA2ALDH1A1CA12 | |
| SCHEMBL19938127 | 0.79 | ALDH1A1 (0.39) | HPGDCA2ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL10917868 | 0.79 | HPGD (0.54) | HPGDTSHRTP53CA1CA2 | |
| SCHEMBL7338642 | 0.78 | CES2 (0.38) | CA1CA2SMN1; SMN2KMT2ACES2 | |
| SCHEMBL7237319 | 0.78 | CES2 (0.38) | HPGDTSHRTP53CA1CA2 | |
| SCHEMBL5857434 | 0.77 | CA12 (0.45) | TSHRTP53CA1CA2ALDH1A1 | |
| SCHEMBL8215216 | 0.76 | MAPT (0.48) | HPGDTSHRCA1CA2ALDH1A1 | |
| SCHEMBL8954661 | 0.76 | MAPT (0.32) | — | |
| SCHEMBL7230535 | 0.75 | NAPRT (0.38) | TP53ALDH1A1SMN1; SMN2KMT2ANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | claimed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | claimed |
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | disclosed |