Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859855 | 0.88 | NPC1 (0.51) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL5862046 | 0.88 | NPC1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5859069 | 0.85 | NPC1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2TSHR | |
| SCHEMBL5859281 | 0.84 | CYP3A4 (0.48) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5862118 | 0.83 | GPR35 (0.46) | MEN1KMT2AMAPTPOLBHSP90AA1 | |
| SCHEMBL5860145 | 0.81 | BRAF (0.49) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL5862164 | 0.74 | GPR35 (0.44) | MAPTSMN1; SMN2HSD17B10NPC1POLB | |
| SCHEMBL5860337 | 0.74 | APOB (0.44) | — | |
| SCHEMBL7064963 | 0.73 | POLB (0.44) | MEN1KMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL5859074 | 0.73 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |