Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858139 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CNR2MAPTHSD17B10MAPK1 | |
| SCHEMBL5859194 | 0.90 | ALDH1A1 (0.50) | ALDH1A1CNR2HSD17B10MAPK1TSHR | |
| SCHEMBL5858104 | 0.90 | RORC (0.51) | ALDH1A1CNR2HSD17B10MAPK1TSHR | |
| SCHEMBL6263830 | 0.83 | ESR1 (0.38) | ALDH1A1CNR2MAPTTSHRKDM4E | |
| SCHEMBL5856893 | 0.83 | CNR2 (0.61) | ALDH1A1CNR2HSD17B10TSHRALOX15 | |
| SCHEMBL5859249 | 0.82 | KIF11 (0.55) | ALDH1A1CNR2HSD17B10TSHRALOX15 | |
| SCHEMBL5856681 | 0.82 | CNR2 (0.51) | ALDH1A1CNR2HSD17B10TSHRALOX15 | |
| SCHEMBL5859317 | 0.81 | RORC (0.53) | ALDH1A1CNR2MAPTHSD17B10TP53 | |
| SCHEMBL5449658 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CNR2MAPTHSD17B10MAPK1 | |
| SCHEMBL5859337 | 0.80 | ANO1 (0.45) | ALDH1A1CNR2MAPTHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071215-B2 | Anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-07-04 | — | — | US | claimed |
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | LEE BYUNG HYUN (US) | 2004-07-01 | — | — | US | claimed |
| US-7071215-B2 | Anthelmintic and insecticidal compositions | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-07-04 | — | — | US | disclosed |
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | LEE BYUNG HYUN (US) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127548-A1 | Novel anthelmintic and insecticidal compositions | ACHE, BCHE, AADAC | ALDH1A1 2781/4885CNR2 1806/4885MAPT 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.