Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726791 | 0.84 | NAAA (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL5043228 | 0.82 | ADRB1 (0.41) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7986084 | 0.80 | SMN1; SMN2 (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4KMT2A | |
| SCHEMBL5859668 | 0.79 | SMN1; SMN2 (0.56) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2769588 | 0.78 | TAS2R14 (0.39) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5726420 | 0.77 | TAS2R14 (0.41) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5727230 | 0.77 | TAS2R14 (0.39) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5726407 | 0.77 | TAS2R14 (0.39) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5725567 | 0.77 | TAS2R14 (0.37) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5726690 | 0.77 | MRGPRX4 (0.39) | AKR1C3PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998423-B2 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. (US) | 2006-02-14 | — | — | US | claimed |