Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726791 | 0.88 | NAAA (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5725348 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5859621 | 0.80 | AKR1C3 (0.43) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5862640 | 0.79 | MRGPRX4 (0.51) | SMN1; SMN2ALDH1A1HPGDPLAAT3PLAAT5 | |
| SCHEMBL5726132 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7986089 | 0.78 | NAAA (0.42) | SMN1; SMN2ALDH1A1KMT2APLAAT3PLAAT5 | |
| SCHEMBL5043616 | 0.78 | PLAAT3 (0.41) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5047954 | 0.77 | PLAAT3 (0.42) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL23417641 | 0.77 | SMN1; SMN2 (0.84) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL5046689 | 0.76 | PLAAT3 (0.41) | SMN1; SMN2ALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |