Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859907 | 0.91 | RAB9A (0.49) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5859859 | 0.90 | TDP1 (0.46) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5859929 | 0.90 | TDP1 (0.41) | NPC1RAB9ASMN1; SMN2TSHRPOLB | |
| SCHEMBL5862246 | 0.85 | CYP2C9 (0.41) | ALDH1A1HPGDRAB9ATSHRNPSR1 | |
| SCHEMBL5859235 | 0.85 | CYP2C9 (0.45) | ALDH1A1HPGDTP53SMN1; SMN2TDP1 | |
| SCHEMBL5858845 | 0.84 | GPR35 (0.47) | ALDH1A1HPGDKDM4EPOLBLMNA | |
| SCHEMBL5859916 | 0.81 | RAB9A (0.49) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5862104 | 0.80 | PLAUR (0.44) | ALDH1A1HPGDTP53RAB9ATSHR | |
| SCHEMBL5859069 | 0.78 | NPC1 (0.46) | ALDH1A1HPGDTP53NPC1RAB9A | |
| SCHEMBL5859258 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |