SCHEMBL586035

SCHEMBL586035

O=C(O)CCc1ccc2c(c1)CC=C2

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.44
PTPRB P23467 1/20 0.43
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43
PTEN P60484 1/20 0.43
PTPMT1 Q8WUK0 1/20 0.43
KEAP1 Q14145 1/20 0.43
FFAR4 Q5NUL3 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 2/20 0.39
P4HTM Q9NXG6 1/20 0.38
CYP26A1 O43174 1/20 0.38
CYP26B1 Q9NR63 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26625541 0.87 FFAR1 (0.44) FFAR1PTPRBCDC25ACDC25BPTEN
SCHEMBL585323 0.83 KDM4E (0.46) CA2
SCHEMBL29482417 0.83 KDM4E (0.46) CA2
SCHEMBL6911329 0.76 CNR1 (0.40) CA2
SCHEMBL20680969 0.74 RXRA (0.57) FFAR1PTPRBCDC25ACDC25BPTEN
SCHEMBL30263704 0.74 RXRA (0.57) FFAR1PTPRBCDC25ACDC25BPTEN
SCHEMBL112142 0.74 TBXAS1 (0.39) FFAR1
SCHEMBL6909899 0.73 SKP2 (0.42) CA1CA2
SCHEMBL81133 0.73
SCHEMBL11111979 0.73 RXRB (0.64) FFAR1KEAP1FFAR4RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3884018-A1 JASMOL Symrise AG (DE) 2021-09-29 EP claimed
CN-113056547-A Jasmine alcohol 西姆莱斯有限公司 2021-06-29 CN claimed
EP-3826986-B1 NOVEL ODORANTS HAVING ROSE ODOUR SYMRISE AG (DE) 2026-03-04 EP disclosed
US-12545851-B2 Fragrances with note of lily of the valley SYMRISE AG (DE) 2026-02-10 US disclosed
EP-4045490-B1 NEW AROMATIC MONOTHIOKETALS AS FRAGRANCES SYMRISE AG (DE) 2025-12-03 EP disclosed
EP-4624559-A2 ISOMER MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS Symrise AG (DE) 2025-10-01 EP disclosed
EP-3684898-B1 METHOD FOR PRODUCING AN ACTIVE SUBSTANCE WAFER SYMRISE AG (DE) 2025-04-30 EP disclosed
EP-4006130-B1 ISOMER MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS SYMRISE AG (DE) 2025-04-09 EP disclosed
EP-3924102-B1 METHOD FOR PRODUCING MICROCAPSULES SYMRISE AG (DE) 2024-12-11 EP disclosed
EP-3969163-B1 BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES SYMRISE AG (DE) 2024-12-11 EP disclosed
EP-4472763-A1 METHOD FOR PRODUCING MICROCAPSULES Symrise AG (DE) 2024-12-11 EP disclosed
WO-2002051375-A1 SELECTION METHOD FOR ODOROUS SUBSTANCES HAARMANN & REIMER GMBH (DE) 2002-07-04 WO disclosed
EP-1215189-A1 Process for the preparation of isolongifolanol HAARMANN & REIMER GMBH (DE) 2002-06-19 EP disclosed
WO-2002024857-A1 MULTI-PHASE SOAP HAARMANN & REIMER GMBH (DE) 2002-03-28 WO disclosed
WO-2002019983-A2 CLEANSING/CONDITIONING AGENTS CONTAINING MATRIX PARTICLES WITH A PERFUME COMPONENT AND A WASHING-ACTIVE COMPONENT HAARMANN & REIMER GMBH (DE) 2002-03-14 WO disclosed
WO-2002012157-A1 NOVEL MACROCYCLIC KETONES HAARMANN & REIMER GMBH (DE) 2002-02-14 WO disclosed
EP-1111029-A2 Perfume compositions containing 4,8-dimethyl-3,7-nonadien-2-one HAARMANN & REIMER GMBH (DE) 2001-06-27 EP disclosed
WO-2001038440-A1 WAX FORMULATIONS CONTAINING ODORIFEROUS SUBSTANCES HAARMANN & REIMER GMBH (DE) 2001-05-31 WO disclosed
WO-2001023373-A2 1,4-DIOXACYCLOALKANE-2-ONE AND 1,4-DIOXACYCLOALKENE-2-ONE HAARMANN & REIMER GMBH (DE) 2001-04-05 WO disclosed
EP-1067126-A2 Tetracyclic acetals HAARMANN & REIMER GMBH (DE) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545851-B2 Fragrances with note of lily of the valley TRPA1, CDY1; CDY1B, TMEM109 FFAR1 1507/4885PTPRB 358/4885CDC25A 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.