Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861897 | 0.88 | ALDH1A1 (0.58) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| Hydrochloric Acid SCHEMBL5862222 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL5861895 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL10723232 | 0.80 | HDAC3 (0.55) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL10723988 | 0.80 | L3MBTL3 (0.56) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL27748909 | 0.79 | HDAC3 (0.55) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL23440304 | 0.77 | ALDH1A1 (0.73) | ALDH1A1TP53L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL10722204 | 0.77 | HDAC3 (0.58) | L3MBTL3L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL15310435 | 0.77 | L3MBTL3 (0.50) | ALDH1A1TP53L3MBTL3L3MBTL1HPGD | |
| SCHEMBL13181087 | 0.76 | HDAC3 (0.67) | ALDH1A1L3MBTL3L3MBTL1HPGDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091247-B2 | Biphenyl compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040106792-A1 | Biphenyl compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1295867-A1 | BIPHENYL COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106792-A1 | Biphenyl compound | GPR4, GPR139, GPR142 | ALDH1A1 1307/4885TP53 2713/4885L3MBTL3 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.