Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TERT | O14746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960549 | 0.91 | L3MBTL1 (0.66) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| Hydrochloric Acid SCHEMBL7970768 | 0.90 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL285298 | 0.88 | SMN1; SMN2 (0.62) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18377765 | 0.86 | L3MBTL1 (0.68) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL1663227 | 0.85 | L3MBTL1 (0.76) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL1928397 | 0.85 | L3MBTL1 (1.00) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL6290094 | 0.85 | L3MBTL1 (0.76) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL9491289 | 0.85 | LMNA (0.83) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL5862258 | 0.83 | L3MBTL1 (0.73) | L3MBTL1NPC1RAB9ALMNATP53BP1 | |
| SCHEMBL15504664 | 0.83 | SMN1; SMN2 (0.57) | L3MBTL1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091247-B2 | Biphenyl compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040106792-A1 | Biphenyl compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1295867-A1 | BIPHENYL COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106792-A1 | Biphenyl compound | GPR4, GPR139, GPR142 | L3MBTL1 2907/4885NPC1 1997/4885RAB9A 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.