Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788798 | 0.82 | — | — | |
| SCHEMBL31413695 | 0.80 | KDM4E (0.37) | KDM4ETDP1 | |
| SCHEMBL379708 | 0.79 | KDM4E (0.32) | TP53KDM4ELMNANPC1RAB9A | |
| SCHEMBL131503 | 0.77 | KDM4E (0.64) | TP53KDM4ELMNACCR1CCR5 | |
| Charcoal, Activated SCHEMBL30558882 | 0.76 | KDM4E (0.31) | TP53KDM4ELMNANPC1RAB9A | |
| SCHEMBL16731967 | 0.73 | ALDH1A1 (0.32) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL3406541 | 0.73 | TP53 (0.46) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL812825 | 0.73 | TDP2 (0.41) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL32679295 | 0.72 | CYP1A2 (0.47) | KDM4ELMNACYP1A2NPC1RAB9A | |
| SCHEMBL23883043 | 0.71 | TP53 (0.34) | TP53KDM4ELMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240349602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-10-17 | — | — | US | claimed |
| US-20240349602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-10-17 | — | — | US | disclosed |
| CN-116496493-B | Polymer, composition for organic EL element, and method for producing same | 三菱化学株式会社 | 2024-09-06 | — | — | CN | disclosed |
| CN-117757067-A | Polymer, composition for organic EL element, and method for producing same | 三菱化学株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-117757066-A | Polymer, composition for organic EL element, and method for producing same | 三菱化学株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-111868140-B | Polymer, composition for organic EL element, and method for producing same | 三菱化学株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-116496493-A | Polymer, composition for organic EL element, and method for producing same | 三菱化学株式会社 | 2023-07-28 | — | — | CN | disclosed |
| US-9242961-B2 | Aurora kinase modulators and method of use | AMGEN INC. (US) | 2016-01-26 | — | — | US | disclosed |
| EP-1984353-B1 | AURORA KINASE MODULATORS AND METHOD OF USE | AMGEN INC (US) | 2015-12-30 | — | — | EP | disclosed |
| CN-101405282-B | Aurora kinase modulators and methods of use | AMGEN INC | 2015-03-25 | — | — | CN | disclosed |
| US-20070213325-A1 | Multi-cyclic compound and method of use | AMGEN INC. (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2007100646-A1 | MULTI-CYCLIC COMPOUNDS AND METHOD OF USE | AMGEN INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20070185111-A1 | Aurora kinase modulators and method of use | AMGEN INC. | 2007-08-09 | — | — | US | disclosed |
| EP-1090000-A4 | NAPHTHO 1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1089729-A4 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001029045-A1 | GRAM-POSITIVE SELECTIVE ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2001-04-26 | — | — | WO | disclosed |
| EP-1090000-A1 | NAPHTHO 1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1089729-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999066927-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067242-A1 | NAPHTHO[1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | MERCK & CO., INC. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185111-A1 | Aurora kinase modulators and method of use | AURKC, AURKA, CDK1 | TP53 156/4885KDM4E 1519/4885LMNA 637/4885 |
| US-20070213325-A1 | Multi-cyclic compound and method of use | TIE1, CDK1, CCNB1 | TP53 456/4885KDM4E 397/4885LMNA 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.