Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053028 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1TP53ALOX15 | |
| SCHEMBL10550712 | 0.81 | DPP4 (0.41) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL4048685 | 0.78 | LTA4H (0.54) | ALDH1A1KMT2AMEN1KDM4EPPARG | |
| SCHEMBL361451 | 0.76 | KDM4E (0.44) | ALDH1A1KMT2AMEN1ALOX15KDM4E | |
| SCHEMBL9450326 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1TP53MAPK1 | |
| Acetic Acid SCHEMBL367778 | 0.76 | KDM4E (0.45) | ALDH1A1KMT2AMEN1TP53MAPK1 | |
| SCHEMBL14646178 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1TP53ALOX15 | |
| SCHEMBL5057664 | 0.75 | KMT2A (0.46) | ALDH1A1KMT2AMEN1TP53ALOX15 | |
| SCHEMBL1520751 | 0.74 | KMT2A (0.71) | ALDH1A1KMT2AMEN1TP53ALOX15 | |
| SCHEMBL14645313 | 0.74 | KMT2A (0.45) | ALDH1A1KMT2AMEN1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034187-B2 | Poly(aralkyl ketone)s and methods of preparing the same | AGENCY FOR SCIENCE, TECHNOLOGY, AND RESEARCH (SG) | 2006-04-25 | — | — | US | claimed |
| US-20050272905-A1 | NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2005-12-08 | — | — | US | claimed |
| US-7034187-B2 | Poly(aralkyl ketone)s and methods of preparing the same | AGENCY FOR SCIENCE, TECHNOLOGY, AND RESEARCH (SG) | 2006-04-25 | — | — | US | disclosed |
| US-20050272905-A1 | NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272905-A1 | NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME | ADSL, KHK, PKLR | ALDH1A1 1700/4885KMT2A 1046/4885MEN1 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.