SCHEMBL5867308

SCHEMBL5867308

O=C1CCCCCCCCC=CCCCCO1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.70
CA9 Q16790 2/20 0.70
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
GLS O94925 3/20 0.37
ATM Q13315 2/20 0.35
SHH Q15465 3/20 0.35
FKBP4 Q02790 3/20 0.35
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789754 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL15577080 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL22759100 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL1539181 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL1539182 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL8465823 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL23438526 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL22985856 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL21983880 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
SCHEMBL21886528 1.00 CA1 (0.70) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006130-B1 ISOMER MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS SYMRISE AG (DE) 2025-04-09 EP disclosed
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) 2025-02-06 US disclosed
EP-4433451-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF Ecole Nationale Supérieure de Chimie de Rennes (FR) 2024-09-25 EP disclosed
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts UMICORE AG & CO. KG (DE) 2024-04-16 US disclosed
US-11807617-B2 Highly efficient synthesis of Z-macrocycles using stereoretentive, ruthenium-based metathesis catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-11-07 US disclosed
WO-2023088919-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES (FR) 2023-05-25 WO disclosed
US-20230159426-A1 LILY OF THE VALLEY ODORANT FIRMENICH & CIE (CH) 2023-05-25 US disclosed
CN-110536748-B Highly efficient synthesis of Z-macrocycles using stereosretentive ruthenium-based metathesis catalysts 加利福尼亚技术学院 2023-04-04 CN disclosed
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2022-02-24 US disclosed
EP-3167031-B1 ISOMERS MIXTURES OF UNSATURATED MACROCYCLIC MUSK COMPOUNDS SYMRISE AG (DE) 2022-02-09 EP disclosed
US-20050131233-A1 Ruthenium compounds, their production and use UNIVERSITY OF OTTAWA (CA) 2005-06-16 US disclosed
WO-2005012315-A1 RUTHENIUM COMPOUNDS, THEIR PRODUCTION AND USE UNIVERSITY OF OTTAWA (CA) 2005-02-10 WO disclosed
EP-0975622-B1 SELECTIVE OLEFIN METATHESIS OF BIFUNCTIONAL OR POLYFUNCTIONAL SUBSTRATES IN COMPRESSED CARBON DIOXIDE AS REACTION MEDIUM STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-10-09 EP disclosed
EP-0908455-B1 Macrocycles GIVAUDAN SA (CH) 2002-07-10 EP disclosed
US-6348551-B1 CATALYTIC CYCLIZATION OF ALKENES AND ALKYNES; ESTERIFICATION, LACTONIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-02-19 US disclosed
US-6255276-B1 MUSK MACROMOLECULE GIVAUDEN ROURE (INTERNATIONAL) S.A. (CH) 2001-07-03 US disclosed
EP-1036081-A1 HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS Ciba SC Holding AG (CH) 2000-09-20 EP disclosed
US-5936100-A METAL CARBENE COMPLEXES OF RUTHENIUM OR OSMIUM STUDIENGESELLSCHAFT KOHLE MBH (DE) 1999-08-10 US disclosed
WO-1999029701-A1 HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-06-17 WO disclosed
EP-0908455-A1 Macrocycles GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1999-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131233-A1 Ruthenium compounds, their production and use TIPARP, SPR, PARP14 CA1 3007/4885CA9 2903/4885ALDH1A1 775/4885
US-20230159426-A1 LILY OF THE VALLEY ODORANT ACLY, PIR, NOX5 CA1 2818/4885CA9 2054/4885ALDH1A1 903/4885
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS MDK, MTR, MUSK CA1 3731/4885CA9 4627/4885ALDH1A1 1302/4885
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF SQLE, SYMPK, FDFT1 CA1 3854/4885CA9 3932/4885ALDH1A1 1256/4885
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts SYMPK, MDK, HCK CA1 3425/4885CA9 4333/4885ALDH1A1 3382/4885
US-11807617-B2 Highly efficient synthesis of Z-macrocycles using stereoretentive, ruthenium-based metathesis catalysts ZKSCAN2, ZYX, SPR CA1 1763/4885CA9 1898/4885ALDH1A1 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.