SCHEMBL5870558

SCHEMBL5870558

Cc1ccc(S(=O)(=O)OCc2cccc(C)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
LMNA P02545 3/20 0.47
CYP19A1 P11511 1/20 0.46
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
MAOB P27338 4/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
MAOA P21397 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4947525 0.93 CYP19A1 (0.53) IDO1LMNACYP19A1L3MBTL1CA1
Toluene SCHEMBL9257721 0.87 CA9 (0.51) LMNAHTTL3MBTL1CA1CA2
SCHEMBL8993345 0.86 LMNA (0.50) IDO1LMNACYP19A1TDP1MAPT
SCHEMBL776918 0.86 ALDH1A1 (0.50) IDO1CYP19A1CA1CA2CA9
SCHEMBL8993165 0.85 PKM (0.52) IDO1LMNAHTTL3MBTL1BCHE
SCHEMBL2890 0.85 CA9 (0.53) LMNAHTTL3MBTL1CA1CA2
SCHEMBL8434488 0.84 IDO1 (0.47) IDO1LMNACYP19A1HTTTDP1
Ammonia Solution, Strong SCHEMBL9470841 0.83 CA9 (0.51) LMNAHTTL3MBTL1CA1CA2
SCHEMBL2551504 0.83 CYP1A2 (0.61) LMNACYP19A1HTTBCHEACHE
SCHEMBL17128399 0.83 TP53 (0.42) LMNACYP19A1TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US claimed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US disclosed
US-20030187178-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2003-10-02 US disclosed
US-6613863-B2 Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts DEGUSSA AG (DE) 2003-09-02 US disclosed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US disclosed