SCHEMBL5871801

SCHEMBL5871801

COC(=O)C(=Cc1cc[c]cc1)C(=O)OC

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
HPGD P15428 1/20 0.49
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13552273 0.86 MAPT (0.56) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL11636094 0.84 KMT2A (0.46) MAPTMEN1KMT2ALMNA
SCHEMBL77732 0.82 MEN1 (0.63) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL5871662 0.80 MAPT (0.45) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL5872078 0.80 MEN1 (0.72) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL11504105 0.79 ALDH1A1 (0.51) MAPTHPGDMEN1KMT2ALMNA
SCHEMBL11504106 0.79 ALDH1A1 (0.51) MAPTHPGDMEN1KMT2ALMNA
SCHEMBL8138421 0.78 MAPT (0.50) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL3519645 0.78 KDM4E (0.62) MAPTHPGD
SCHEMBL5871929 0.78 KMT2A (0.54) MAPTMEN1KMT2ANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US claimed
US-5241067-A Imparting heat, light and oxidation resistance to polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-31 US claimed
CN-1266151-C Naphthyridine derivatives OTSUKA PHARMA CO LTD (JP) 2006-07-26 CN disclosed
US-7071187-B2 Naphthyridine derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2006-07-04 US disclosed
CN-1547581-A Naphthyridine derivatives 株式会社大V制药工场 2004-11-17 CN disclosed
US-20040214853-A1 Naphthyridine derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-10-28 US disclosed
EP-1426374-A1 NAPHTHYRIDINE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-06-09 EP disclosed
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US disclosed
US-5408008-A Piperidinyl phthalimide hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-04-18 US disclosed
US-5241067-A Imparting heat, light and oxidation resistance to polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-31 US disclosed
EP-0294818-A2 Hindered amine light stabilizers containing aromatic carboxy groups and derivatives ELF ATOCHEM NORTH AMERICA, INC. (US) 1988-12-14 EP disclosed
US-4159270-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-06-26 US disclosed
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4075162-A BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4070337-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214853-A1 Naphthyridine derivatives MT-ND1, OPRD1, NR0B1 MAPT 2184/4885HPGD 1690/4885MEN1 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.