Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872453 | 0.95 | — | — | |
| SCHEMBL5872282 | 0.72 | — | — | |
| SCHEMBL9119329 | 0.70 | PLA2G7 (0.31) | — | |
| SCHEMBL9578310 | 0.68 | HSD17B10 (0.33) | — | |
| SCHEMBL6167979 | 0.61 | MEN1 (0.36) | — | |
| SCHEMBL37783 | 0.60 | EPHX1 (0.52) | — | |
| SCHEMBL3373268 | 0.60 | EPHX1 (0.52) | — | |
| SCHEMBL10589508 | 0.60 | EPHX1 (0.52) | — | |
| SCHEMBL3369909 | 0.60 | EPHX1 (0.52) | — | |
| SCHEMBL7110706 | 0.60 | EPHX1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153921-B2 | Synthesis of elastomeric carborane-siloxanes by hydrosilation reactions | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2006-12-26 | — | — | US | disclosed |
| US-7109259-B2 | Piperazinone derivatives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050171317-A1 | Synthesis of elastomeric carborane-siloxanes by hydrosilation reactions | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE | 2005-08-04 | — | — | US | disclosed |
| US-20030027902-A1 | Piperazinone derivatives | LAZZARI DARIO (IT) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027902-A1 | Piperazinone derivatives | H1-4, EIF4G1, GPX4 | MAPT 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.