Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643676 | 0.89 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL635165 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL29739404 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL717613 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL29036560 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL1424440 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL6383570 | 0.80 | GPR35 (0.65) | ALDH1A1HSD17B10GPR35HIF1AKMT2A | |
| SCHEMBL14744561 | 0.80 | ALDH1A1 (0.74) | ALDH1A1HSD17B10GPR35CYP19A1HIF1A | |
| SCHEMBL29739338 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 | |
| SCHEMBL28291579 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10GPR35TSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11919921-B2 | Galactoside inhibitor of galectins | GALECTO BIOTECH AB (DK) | 2024-03-05 | — | — | US | disclosed |
| US-20220289783-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2022-09-15 | — | — | US | disclosed |
| US-11377464-B2 | Galactoside inhibitor of galectins | GALECTO BIOTECH AB (DK) | 2022-07-05 | — | — | US | disclosed |
| CN-113621005-A | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-107406478-B | alpha-D-galactoside inhibitors of galectins | 格莱克特生物技术公司 | 2021-07-27 | — | — | CN | disclosed |
| EP-3828191-A2 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | Galecto Biotech AB (DK) | 2021-06-02 | — | — | EP | disclosed |
| EP-3250581-B1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2021-01-20 | — | — | EP | disclosed |
| US-20200407391-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2020-12-31 | — | — | US | disclosed |
| US-10774102-B2 | Galactoside inhibitor of galectins | GALECTO BIOTECH AB (DK) | 2020-09-15 | — | — | US | disclosed |
| US-20170349619-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2017-12-07 | — | — | US | disclosed |
| WO-2016120403-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2016-08-04 | — | — | WO | disclosed |
| US-7098338-B2 | 2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a) quinoxalin-5(6H)one derivatives | WYETH (US) | 2006-08-29 | — | — | US | disclosed |
| US-20040116437-A1 | 2,3,4,4a-tetrahydro-1H-pyrazino(1,2-a) quinoxalin-5(6H)one derivatives | WYETH (US) | 2004-06-17 | — | — | US | disclosed |
| US-6706714-B2 | USEFUL FOR THE TREATMENT OF DISORDERS INVOLVING THE CENTRAL NERVOUS SYSTEM SUCH AS OBSESSIVE-COMPULSIVE DISORDER, DEPRESSION, ANXIETY, SCHIZOPHERNIA, MIGRAINE, SLEEP OR EATING DISORDER, OBESITY, TYPE II DIABETES AND EPILEPSY | WYETH CORP (US) | 2004-03-16 | — | — | US | disclosed |
| US-20030060468-A1 | 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)one derivatives | WYETH (US) | 2003-03-27 | — | — | US | disclosed |
| US-6476032-B2 | 5HT2C RECEPTOR AGONISTS TO TREAT SCHIZOPHRENIA AND CENTRAL NERVOUS SYSTEM DISORDERS; OBSESSIVE-COMPULSIVE DISORDER; ANTIDEPRESSANTS, MIGRAINE; SLEEP DISORDERS; EATING DISORDERS; OBESITY; ANTIDIABETIC, -EPILEPTIC AND ANXIOLYTIC AGENTS | WYETH | 2002-11-05 | — | — | US | disclosed |
| US-6372745-B1 | TREATMENT OF OBESITY IN MAMMALS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-16 | — | — | US | disclosed |
| US-20010051622-A1 | 2,3,4,4a-tetrahydro-1H-pyrazino-[1,2a] quinoxalin-5- (6H) one derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-12-13 | — | — | US | disclosed |
| EP-1140940-A1 | 2,3,4,4A-TETRAHYDRO-1H-PYRAZINO(1,2-A)QINOXALIN-5(6H)ONE DERIVATES BEING 5HT2C AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035922-A1 | 2,3,4,4A-TETRAHYDRO-1H-PYRAZINO(1,2-A)QUINOXALIN-5(6H)ONE DERIVATES BEING 5HT2C AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407391-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | LGALS1, LGALS3, LGALS2 | ALDH1A1 1785/4885HSD17B10 3212/4885GPR35 986/4885 |
| US-11377464-B2 | Galactoside inhibitor of galectins | LGALS3, LGALS1, LGALS2 | ALDH1A1 1974/4885HSD17B10 3578/4885GPR35 1058/4885 |
| US-11919921-B2 | Galactoside inhibitor of galectins | LGALS3, LGALS1, LGALS2 | ALDH1A1 1974/4885HSD17B10 3578/4885GPR35 1058/4885 |
| US-20030060468-A1 | 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)one derivatives | NPY2R, HCRTR2, HTR2C | ALDH1A1 1969/4885HSD17B10 1873/4885GPR35 211/4885 |
| US-20220289783-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | LGALS1, LGALS3, LGALS2 | ALDH1A1 1785/4885HSD17B10 3212/4885GPR35 986/4885 |
| US-20010051622-A1 | 2,3,4,4a-tetrahydro-1H-pyrazino-[1,2a] quinoxalin-5- (6H) one derivatives | HTR2C, HTR3C, NPY2R | ALDH1A1 2135/4885HSD17B10 1944/4885GPR35 225/4885 |
| US-20170349619-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | LGALS3, LGALS1, LGALS2 | ALDH1A1 1252/4885HSD17B10 3659/4885GPR35 1471/4885 |
| US-10774102-B2 | Galactoside inhibitor of galectins | LGALS3, LGALS1, LGALS2 | ALDH1A1 1974/4885HSD17B10 3578/4885GPR35 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.