SCHEMBL5872606

SCHEMBL5872606

O=S(=O)(OS(c1ccccc1)(c1ccccc1)c1ccccc1)C(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.36
HTR6 P50406 1/20 0.35
APOBEC3G Q9HC16 1/20 0.34
ALDH1A1 P00352 3/20 0.33
NR1H3 Q13133 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA5A P35218 2/20 0.33
CA9 Q16790 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33
PLA2G7 Q13093 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15224311 0.85 NR1H3 (0.40) HSD11B1ALDH1A1NR1H3TSHRNR1I2
SCHEMBL7708209 0.76 HSD11B1 (0.34) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL37033 0.75 HTR6 (0.42) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL4377114 0.73 CA1 (0.35) CA1CA2CA9
SCHEMBL482039 0.71 HSD11B1 (0.36) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL2437767 0.70 HTR6 (0.38) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL6291307 0.70 HTR6 (0.38) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL962839 0.70 HSD11B1 (0.41) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL217002 0.70 HTR6 (0.38) HSD11B1HTR6APOBEC3GALDH1A1NR1H3
SCHEMBL2391334 0.68 HSD11B1 (0.34) HSD11B1NR1H3TSHRNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125653-B2 Method of producing conductive or semiconducting structured polymers INFINEON TECHNOLOGIES AG (DE) 2006-10-24 US disclosed
US-20030027079-A1 Method of producing conductive or semiconducting structured polymers POLARIS INNOVATIONS LIMITED (IE) 2003-02-06 US disclosed