Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 8/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | RORA | P35398 | 2/20 | 0.36 |
| ▸ | RORB | Q92753 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872606 | 0.85 | HSD11B1 (0.36) | NR1H3HSD11B1TSHRNR1H2NR1I2 | |
| SCHEMBL37033 | 0.71 | HTR6 (0.42) | NR1H3HSD11B1TSHRNR1H2ALDH1A1 | |
| SCHEMBL962839 | 0.70 | HSD11B1 (0.41) | NR1H3HSD11B1TSHRNR1H2ABCC9 | |
| SCHEMBL3791469 | 0.69 | HSD11B1 (0.41) | NR1H3HSD11B1TSHRNR1H2ABCC9 | |
| SCHEMBL7708209 | 0.69 | HSD11B1 (0.34) | NR1H3HSD11B1TSHRNR1H2MEN1 | |
| SCHEMBL1634800 | 0.68 | HSD11B1 (0.39) | NR1H3HSD11B1TSHRPOLBMAPK1 | |
| SCHEMBL965951 | 0.68 | CA1 (0.39) | NR1H3HSD11B1TSHRNR1H2ABCC9 | |
| SCHEMBL2391334 | 0.68 | HSD11B1 (0.34) | NR1H3HSD11B1TSHRNR1H2ABCC9 | |
| SCHEMBL482039 | 0.68 | HSD11B1 (0.36) | NR1H3HSD11B1TSHRPOLBMAPK1 | |
| SCHEMBL2437767 | 0.67 | HTR6 (0.38) | NR1H3HSD11B1TSHRNR1H2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2634631-A1 | Acid generator, chemically amplified resist composition, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |