Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 6/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083191 | 0.89 | KEAP1 (0.43) | KEAP1NFE2L2TOP2ATOP2BCYP2C9 | |
| SCHEMBL8132915 | 0.87 | KEAP1 (0.41) | KEAP1NFE2L2TOP2ATOP2BCYP2C9 | |
| SCHEMBL10330770 | 0.86 | TOP2A (0.45) | TOP2ATOP2BCYP2C9LMNAATP6V1B2 | |
| SCHEMBL8120501 | 0.84 | TOP2A (0.36) | KEAP1NFE2L2TOP2ATOP2BCYP2C9 | |
| SCHEMBL501306 | 0.84 | KMT2A (0.46) | TOP2ATOP2BLMNAKDM4EKMT2A | |
| SCHEMBL1444489 | 0.83 | KEAP1 (0.49) | KEAP1NFE2L2TOP2ATOP2BCYP2C9 | |
| SCHEMBL9775979 | 0.82 | TOP2A (0.37) | KEAP1NFE2L2TOP2ATOP2BCYP2C9 | |
| SCHEMBL9685735 | 0.80 | LMNA (0.43) | TOP2ATOP2BCYP2C9LMNAATP6V1B2 | |
| SCHEMBL9684716 | 0.80 | LMNA (0.43) | TOP2ATOP2BCYP2C9LMNAATP6V1B2 | |
| SCHEMBL6241091 | 0.80 | LMNA (0.63) | KEAP1NFE2L2CYP2C9LMNAATP6V1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775114-B1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | PROCTER & GAMBLE (US) | 2000-03-22 | — | — | EP | claimed |
| US-5703231-A | Process for making antimicrobial compounds | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| CN-1158120-A | Process for the preparation of antimicrobial compounds | PROCTER & GAMBLE (US) | 1997-08-27 | — | — | CN | claimed |
| US-7012144-B2 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-14 | — | — | US | disclosed |
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-07-10 | — | — | US | disclosed |
| EP-0677050-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL JEDANG CORP (KR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0775114-B1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | PROCTER & GAMBLE (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0401623-B1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| CN-1042632-C | Novel pyridone carboxylic acid derivatives | NO 1 SUGAR REFINING CO LTD (KR) | 1999-03-24 | — | — | CN | disclosed |
| US-5723627-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5703231-A | Process for making antimicrobial compounds | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| CN-1158120-A | Process for the preparation of antimicrobial compounds | PROCTER & GAMBLE (US) | 1997-08-27 | — | — | CN | disclosed |
| US-5648493-A | MULTISTAGE PROCESS BY CONDENSING AN OXO COMPOUND WITH AN AMINO COMPOUND TO PRODUCE AN IMINE THEN REACTING WITH AN OXO QUINOLINE CARBOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| EP-0775114-A1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5527910-A | BACTERICIDES; STAPHYLOCOCCUS, STREPTOCOCCUS INFECTIONS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1996-06-18 | — | — | US | disclosed |
| WO-1996004247-A1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0677050-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL FOODS & CHEMICALS, INC. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994015933-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-07-21 | — | — | WO | disclosed |
| US-5061712-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0401623-A1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | CYCS, CBR3, HCCS | KEAP1 184/4885NFE2L2 1216/4885TOP2A 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.