Malonic Acid

Malonic Acid

SCHEMBL5874902

Cc1ccccc1C(C)(C)N.O=C(O)CC(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RBP4 P02753 2/20 0.39
ITGB3 P05106 2/20 0.39
ITGAV P06756 2/20 0.39
ITGB1 P05556 1/20 0.39
ITGA5 P08648 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
POLB P06746 2/20 0.38
CTNNB1 P35222 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL5179943 0.89 CYP2C19 (0.39) GAAALDH1A1KDM4EATMNPSR1
Succinic Acid SCHEMBL5874073 0.89 NR4A2 (0.41) GAAALDH1A1KDM4EATMNPSR1
Propionic Acid SCHEMBL5874238 0.89 HIF1A (0.39) GAAALDH1A1KDM4EATMNPSR1
Bicarbonate SCHEMBL5874331 0.89 KMT2A (0.41) GAAALDH1A1KDM4EATMNPSR1
Chloroacetic Acid SCHEMBL5874302 0.88 HIF1A (0.38) GAAALDH1A1KDM4EATMNPSR1
Itaconate SCHEMBL5875309 0.88 ALOX15 (0.39) GAAALDH1A1KDM4EATMNPSR1
Oxalic Acid SCHEMBL5179301 0.87 ALDH1A1 (0.44) GAAALDH1A1KDM4EATMNPSR1
Oxalic Acid SCHEMBL153610 0.87 ALDH1A1 (0.44) GAAALDH1A1KDM4EATMNPSR1
Acetic Acid SCHEMBL1047016 0.87 HPGD (0.40) GAAALDH1A1KDM4EATMNPSR1
Adipic Acid SCHEMBL5874263 0.86 HPGD (0.45) ALDH1A1KDM4EATMNPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed